Antigen-presenting cell activation requires intrinsic and extrinsic STING signaling after the phagocytosis of DNA-damaged cells

Summary ♦️Phagocytes are generally capable of en- gulfing and eliminating apoptotic cells without initiating the CGAS-STING path- ways that are triggered by cytosolic dou- ble-stranded DNA. ♦️ How phagocytes are therefore able to detect DNA-damaged cells that are potentially precancerous or virally infected is not well understood. Park et al. report that DNA-damaged cells initiate … Read more

MSD Enters into Exclusive Global License Agreement with Hansoh Pharma for Investigational Oral GLP-1 Receptor Agonist

✨Continue to leverage science-driven business development to augment and complement our robust pipeline, said Dr.Dean Y.Li, president, MSD Research Laboratories.“Through this agreement, we aim to build on our experience targeting incretin biology to evaluate HS-10535 and its potential to provide additional cardiometabolic benefits beyond weight reduction.” ✨Under the agreement, Hansoh Pharma has granted MSD an … Read more

Prevent Harm: 5 Key Food-Drug Interactions

✨ Did you know that certain foods can interact with medications and reduce their effectiveness or cause harmful side effects? Being aware of these interactions is crucial for safe medication use. Here are the top 5 food-drug interactions you should be mindful of to keep your health on track.🍞 1. Milk and Antibiotics🥛 🔹Interaction: Reduces … Read more

Scientists have found a way to help the brain learn faster using Al to guide brain activity directly🧠

Here’s how it works; ~Participants were placed in an fMRI machine, where they saw abstract shapes that “wobbled” on a screen. The wobbling was controlled by their brain activity. When their brain activity matched a specific pattern, the wobbling stopped. This feedback helped guide their brain toward learning something new without them even realizing it. … Read more

Cabozantinib API: The Competitive Edge for Your Developments

➤Cabozantinib S-malate Crystalline form N2 (Innovator form). ➤Cabozantinib HCI – An alternate salt providing 505(b)(2) opportunities in the US and early launch opportunities in Europe, Brazil, Turkey, Mexico, South Korea, and many other countries. ➤Particle Size Distribution (PSD) – D (90) < 25 Micron, with customized PSDs available based on customer needs. ➤ Quality by … Read more

Microplastics Discovered in Human Brain Tissue: What Are The Health Risks?

🧠From the air we breathe to the water we drink, microplastics infiltrate every corner of our lives—but what happens when they cross into our brains? 💨Plastic is all around us: your water bottle, makeup, car, and food packaging likely have at least some plastic components, but what about your dinner? Or the ocean? Or the … Read more

The Future of Cancer Diagnosis and Treatment:
Spotlight on Cancer Biomarkers- IndustryARC™™

♦️Global cancer biomarkers market is projected to grow from USD 24.5 billion in 2024 to USD 42.0 billion by 2029, demonstrating a robust CAGR of 11.3% during forecast period 2024-2030. 🔷Cancer biomarkers are biological molecules found in #blood,#tissues, or other body fluids that indicate the presence, progression, or characteristics of cancer in the body. These #biomarkers … Read more

“FDA Approves Drug to Reduce Triglycerides in Adult Patients with Familial Chylomicronemia Syndrome (first-in-class approval)”

♦️The U.S. Food and Drug Administration has approved Tryngolza(olezarsen), used with diet, to reduce triglycerides (TG)  in adults with familial chylamicronemia syndrome (FCS). This is a first-in-class approval, meaning Tryngolza uses a new mechanism of action, or works differently in the body, than other therapies currently used to treat FCS. ♦️ Disease or condition; 🔹FCS is … Read more

Russia has announced the development of its own mRNA-based cancer vaccine,

♦️Russia has announced the development of its own mRNA-based cancer vaccine, scheduled for public release in early 2025 and to be provided free of charge to patients. 📌Pre-clinical trials have shown promising results, suggesting that the vaccine effectively suppresses tumor growth and reduces the potential for metastasis. 📌 These trials, typically conducted in laboratory settings … Read more

🌞Vitamin D Deficiency: The Silent Epidemic

🔷Did you know that Vitamin D deficiency is one of the most underdiagnosed yet widespread health concerns globally? This “sunshine vitamin” plays a critical role in bone health, immunity, and even mental well-being, but millions are still at risk due to modern lifestyles. 🌞Why Are We deficient ? *Lack of Sun Exposure Spending more time … Read more